Peptide Database

Peptide NameBmKDfsin4-4RS/K13R/R32S analog

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC166H243N49O53S6

DescriptionStandard

        GFGCPFNQGQCHRHCQSISSSGGYCDGFLKTSCVCYS
    

Molecular Weight3965.39 Da

Isoelectric Point (pI)7.79

Net Charge (pH 7.0)0.87

Net Charge (pH 7.4) 0.48

Charge Density (pH 7.0) 0.0236

GRAVY Index-0.23

Hydrophobic Moment 0.47

Boman Index0.06

Instability Index61.05

Aliphatic Index 28.92

Aromaticity 0.1351

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1639.14

LogP -24.10

H-bond Donors 63.0

H-bond Acceptors 62.0

Rotatable Bonds 125.0

Heavy Atoms 274.0

Ring Count 8.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416883 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsAPD analysis reveals that this sequence is similar (83.78%) to BmKDfsin4 S=C=G: 16%. Chemical modification: 3 disulfide bonds

Bio-Activity Profile

Function

Antimicrobial

TargetStaphylococcus aureus ATCC6538