Peptide Database

Peptide NameMaximins y Hv type 2 [Cleaved into: Maximin-y

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length142 amino acids

Chemical FormulaC688H1127N197O211S3

DescriptionStandard

        MNFKYIVAVSFLITSGYARSVKNDEQSLSQRDVLEEESLREIRGIGGALLSAGKAALKGLAKGFAEHFGKRTAEDHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQEEIANLFTKKEKRILGPVLSLVGSALGGLIKKIG
    

Molecular Weight15630.70 Da

Isoelectric Point (pI)6.85

Net Charge (pH 7.0)-0.20

Net Charge (pH 7.4) -0.62

Charge Density (pH 7.0) -0.0014

GRAVY Index-0.32

Hydrophobic Moment 0.65

Boman Index-0.05

Instability Index39.88

Aliphatic Index 94.15

Aromaticity 0.0563

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6632.26

LogP -65.62

H-bond Donors 232.0

H-bond Acceptors 217.0

Rotatable Bonds 550.0

Heavy Atoms 1099.0

Ring Count 13.0

Amide Bonds 148.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0347263 VERIFIED: NO

Provenance & Taxonomy

OrganismBombina maxima [Animal]

FamilyBombinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Antifungal Fungicide Anti-Candida Cytolytic Hemolytic Non-ribosomal

MethodQualitative functional evidence