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MYP_113438
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Basic Information
Alloferon-1 (Insects, animals)
Anticancer
Anticancer ▸ Antitumor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Enzyme modulation ▸ Enzyme inhibition ▸ Reactivation inhibitor
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Standard
13 amino acids
C52H76N22O16
Standard
Sequence
HGVSGHGQHGVHG
Physicochemical Analysis
1265.30 Da
7.10
0.11
-0.30
0.0084
-0.82
0.26
0.15
-22.68
44.62
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
590.56
-9.19
20.0
20.0
39.0
90.0
4.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0147486 VERIFIED: NO
Provenance & Taxonomy
Blow fly [Animal]; Insecta [Animal]
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0160089 VERIFIED: YES
Provenance & Taxonomy
Calliphora vicina [Animal]
Alloferon
7370
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Skin cancer (cell line not reported)
PaperCancerPPD2 curated year-page record; primary PMID 12235362 (2002), additional curated PMID 18957441. PMID12235362;18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12235362/
RECORD: Rec_0160826 VERIFIED: YES
Provenance & Taxonomy
Calliphora vicina [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer Antiviral
Evidence URLhttps://patents.google.com/patent/US20070293424A1/en PatentUS 2007/0293424 A1
RECORD: Rec_0167263 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Blow fly [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
allo-residue reported
Bio-Activity Profile
Antimicrobial Antiviral Anticancer
Staphylococcus aureus ATCC 25923 or penicillin-resistant
16-64 μg/mL
MIC
PaperNovel antiviral and antitumoral peptides from insects.
RECORD: Rec_0192722 VERIFIED: YES
Provenance & Taxonomy
Calliphora vicina [Animal]
Alloferon
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Anticancer
PaperProc Natl Acad Sci U S A 2002; 99 (20):12628-32 | http://www.ncbi.nlm.nih.gov/pubmed/12235362 PMID12235362 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12235362/
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