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MYP_113438
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Basic Information
Alloferon-1 (Insects, animals)
Anticancer
Anticancer ▸ Antitumor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Enzyme modulation ▸ Enzyme inhibition ▸ Reactivation inhibitor
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Standard
13 amino acids
C52H76N22O16
Standard
Sequence
HGVSGHGQHGVHG
Physicochemical Analysis
1265.30 Da
7.10
0.11
-0.30
0.0084
-0.82
0.26
0.15
-22.68
44.62
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
590.56
-9.19
20.0
20.0
39.0
90.0
4.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0079989 VERIFIED: YES
Provenance & Taxonomy
Calliphora vicina [Animal]
Alloferon
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic Antiviral Anticancer
Human influenza viruses A and B
PaperPubMed PMID: 12235362 PMID12235362 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12235362/
RECORD: Rec_0103691 VERIFIED: NO
Provenance & Taxonomy
Calliphora vicina,Calliphora erythrocephala [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
RECORD: Rec_0114179 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 30.8%, E 0.0%, T 30.8%, C 38.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Antibacterial Antiviral Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0117625 VERIFIED: YES
Provenance & Taxonomy
Calliphora vicina [Animal]
Alloferon
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Reactivation inhibitor
Kaposi's sarcoma-associated herpesvirus (Reactivation); BCBL-1
Thymidine incorporation assay
PaperInhibition of lytic reactivation of Kaposi's sarcoma-associated herpesvirus by alloferon. | Lee N, Bae S, Kim H, Kong JM, Kim HR, Cho BJ, Kim SJ, Seok SH, Hwang YI, Kim S, Kang JS, Lee WJ. | Antivir Ther. 2011 | PMID:21311105 PMID21311105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21311105/
RECORD: Rec_0122383 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Blow fly [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
allo-residue reported
Bio-Activity Profile
Antimicrobial Antiviral Anticancer
Escherichia coli ATCC 25922 or penicillin-resistant
8-16 μg/mL
MIC
PaperNovel antiviral and antitumoral peptides from insects.
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