Peptide Database

Peptide NameMu-agatoxin-Aa1b (Mu-AGTX-Aa1b; Mu-agatoxin II; Mu-agatoxin-2)

Function Ontology

Insecticidal/Pest control ▸ Insecticidal activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC168H255N51O52S9

DescriptionStandard

        ECATKNKRCADWAGPWCCDGLYCSCRSYPGCMCRPSS
    

Molecular Weight4109.72 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.46

Charge Density (pH 7.0) 0.0475

GRAVY Index-0.50

Hydrophobic Moment 0.45

Boman Index-0.13

Instability Index83.34

Aliphatic Index 18.65

Aromaticity 0.1081

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1650.47

LogP -21.01

H-bond Donors 67.0

H-bond Acceptors 63.0

Rotatable Bonds 125.0

Heavy Atoms 280.0

Ring Count 9.0

Amide Bonds 37.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0276042 VERIFIED: YES

Provenance & Taxonomy

OrganismAgelenopsis aperta [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Insecticidal

Targetsexta

Activity75±27 μg/g

MethodLD50

RECORD: Rec_0310767 VERIFIED: NO

Provenance & Taxonomy

OrganismAgelenopsis aperta [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-18; 9-23; 17-33; 25-31

Bio-Activity Profile

Function

Toxin