Peptide Database

Peptide NameAtrial natriuretic factor

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC95H158N36O34S3

DescriptionStandard

        TSGCFGARMDRIGNASGLGCNSGRG
    

Molecular Weight2444.69 Da

Isoelectric Point (pI)9.00

Net Charge (pH 7.0)1.38

Net Charge (pH 7.4) 1.16

Charge Density (pH 7.0) 0.0552

GRAVY Index-0.33

Hydrophobic Moment 0.52

Boman Index-0.05

Instability Index-3.60

Aliphatic Index 39.20

Aromaticity 0.0400

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1151.82

LogP -20.19

H-bond Donors 44.0

H-bond Acceptors 39.0

Rotatable Bonds 82.0

Heavy Atoms 168.0

Ring Count 1.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0381074 VERIFIED: YES

Provenance & Taxonomy

OrganismOreochromis mossambicus [Animal]

FamilyAtrial natriuretic factor

Tax ID8127

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide4-20

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Receptor modulation

Half-LifeMammalian: 7.2 hour; Yeast: >20 hour; E. coli: >10 hour