Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC556H891N149O164S5

DescriptionStandard

        PDLNGHEKYGLGNVKYNISRIRVTAVEFPSASISLLPGTGIKLVIANASLTMDMNWSLRTWMFKDTGRSTVYISKVFATAIFSMPLDPTGHTLISLTSCRTTSGDIDIKLHGKS
    

Molecular Weight12447.25 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)4.21

Net Charge (pH 7.4) 3.97

Charge Density (pH 7.0) 0.0370

GRAVY Index0.03

Hydrophobic Moment 0.53

Boman Index0.11

Instability Index15.10

Aliphatic Index 92.37

Aromaticity 0.0789

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4992.02

LogP -51.92

H-bond Donors 180.0

H-bond Acceptors 176.0

Rotatable Bonds 409.0

Heavy Atoms 874.0

Ring Count 19.0

Amide Bonds 118.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0217718 VERIFIED: NO

Provenance & Taxonomy

OrganismEudromia elegans [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria