Peptide Database

Peptide NameNeuromedin-U-25

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC144H216N42O38

DescriptionStandard

        FKVDEEFQGPIVSQNRRYFLFRPRN
    

Molecular Weight3143.51 Da

Isoelectric Point (pI)9.97

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0706

GRAVY Index-0.97

Hydrophobic Moment 0.42

Boman Index-0.28

Instability Index41.05

Aliphatic Index 54.40

Aromaticity 0.2000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1342.48

LogP -11.34

H-bond Donors 46.0

H-bond Acceptors 40.0

Rotatable Bonds 102.0

Heavy Atoms 224.0

Ring Count 7.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0364966 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyNeuromedin-U

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasoconstrictor Myotropic

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0383615 VERIFIED: NO