Peptide Database

Peptide NameCecropin-A2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length56 amino acids

Chemical FormulaC259H436N78O73

DescriptionStandard

        VFVALILAIAIGQSEAGWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATARG
    

Molecular Weight5810.71 Da

Isoelectric Point (pI)10.43

Net Charge (pH 7.0)3.82

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.0683

GRAVY Index0.28

Hydrophobic Moment 0.94

Boman Index0.15

Instability Index28.28

Aliphatic Index 116.96

Aromaticity 0.0357

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2449.43

LogP -24.39

H-bond Donors 85.0

H-bond Acceptors 78.0

Rotatable Bonds 200.0

Heavy Atoms 410.0

Ring Count 4.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0120149 VERIFIED: NO

Provenance & Taxonomy

OrganismDrosophila yakuba [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence