Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC418H687N123O121S8

DescriptionStandard

        MKLLFLLLVLLLATEPVASGECWMDGHCRLVCKNDEDSISRCRNRKRCCVPSRYLTIQPVTVDGILGWTTAQTPTPDKKTNRNHV
    

Molecular Weight9628.20 Da

Isoelectric Point (pI)8.88

Net Charge (pH 7.0)3.62

Net Charge (pH 7.4) 3.20

Charge Density (pH 7.0) 0.0426

GRAVY Index-0.19

Hydrophobic Moment 0.52

Boman Index-0.06

Instability Index43.16

Aliphatic Index 91.65

Aromaticity 0.0471

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3936.04

LogP -39.37

H-bond Donors 144.0

H-bond Acceptors 135.0

Rotatable Bonds 316.0

Heavy Atoms 670.0

Ring Count 13.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0068626 VERIFIED: NO

Provenance & Taxonomy

OrganismProlemur simus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence