Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC368H612N112O97S8

DescriptionStandard

        MRTAALFFTILFFMSQVLPVRGNLKEICERPNGSCRRYCIQTEIHVGRCLNNRPCCLPLGKQPRIKSTTTKKK
    

Molecular Weight8414.01 Da

Isoelectric Point (pI)10.19

Net Charge (pH 7.0)10.53

Net Charge (pH 7.4) 10.16

Charge Density (pH 7.0) 0.1442

GRAVY Index-0.27

Hydrophobic Moment 0.52

Boman Index-0.12

Instability Index53.22

Aliphatic Index 78.77

Aromaticity 0.0685

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3410.40

LogP -34.07

H-bond Donors 126.0

H-bond Acceptors 117.0

Rotatable Bonds 282.0

Heavy Atoms 585.0

Ring Count 11.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076231 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyDefensin

Tax ID9986

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence