Peptide Database

Peptide NameAurein-1.2 [A10W]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC79H118N16O19

DescriptionStandard

        GLFDIIKKIWESF
    

Molecular Weight1595.88 Da

Isoelectric Point (pI)6.07

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0183

GRAVY Index0.46

Hydrophobic Moment 0.72

Boman Index0.31

Instability Index20.48

Aliphatic Index 120.00

Aromaticity 0.2308

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 575.18

LogP -0.17

H-bond Donors 20.0

H-bond Acceptors 19.0

Rotatable Bonds 53.0

Heavy Atoms 114.0

Ring Count 4.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0083968 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAurein

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetHuman erythrocytes (5% Hemolysis at 25 microg/ml

Activity25 μg/mL

MethodHemolysis

RECORD: Rec_0308013 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAurein

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus ATCC 29213

Activity12.5 μg/mL

MethodMIC