Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length107 amino acids

Chemical FormulaC533H837N147O147S11

DescriptionStandard

        MKTMLFTVALTGPPTSLPPSPLPELLYHINVRDVSHPARDAMSYNMSALGLILITLLLLTAGEANDTDVQGWTCGYRGLCRKHCYAQEYMIGYHGCPRRYRCCALRF
    

Molecular Weight12008.96 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.27

Charge Density (pH 7.0) 0.0261

GRAVY Index0.02

Hydrophobic Moment 0.73

Boman Index0.09

Instability Index48.59

Aliphatic Index 87.57

Aromaticity 0.0935

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16305.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4636.50

LogP -40.38

H-bond Donors 169.0

H-bond Acceptors 165.0

Rotatable Bonds 378.0

Heavy Atoms 838.0

Ring Count 23.0

Amide Bonds 111.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0038331 VERIFIED: NO

Provenance & Taxonomy

OrganismSinocyclocheilus grahami [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal