Peptide Database

Peptide NameCecropin A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC177H302N52O43

DescriptionStandard

        RWKIFKKIEKVGRNIRDGIVKAGPAIEVLGAAKAL
    

Molecular Weight3846.61 Da

Isoelectric Point (pI)10.64

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.54

Charge Density (pH 7.0) 0.1646

GRAVY Index-0.01

Hydrophobic Moment 0.93

Boman Index-0.01

Instability Index50.67

Aliphatic Index 117.14

Aromaticity 0.0571

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1556.53

LogP -10.09

H-bond Donors 55.0

H-bond Acceptors 49.0

Rotatable Bonds 135.0

Heavy Atoms 272.0

Ring Count 4.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124016 VERIFIED: YES

Provenance & Taxonomy

OrganismSpodoptera exigua [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)