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MYP_113266
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Basic Information
Epinecidin-8
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C93H142N22O17S
Standard
Sequence
FIFHIIKGLFHAGKMI
Physicochemical Analysis
1872.32 Da
10.00
1.93
1.63
0.1208
1.18
0.59
0.54
41.29
128.12
0.1875
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
609.22
0.85
21.0
22.0
62.0
133.0
5.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0258568 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0259691 VERIFIED: YES
Provenance & Taxonomy
Epinephelus nebulosus [Animal]
Epinecidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HeLa
6.25 μg/mL
Cytotoxicity assay
PaperTruncated antimicrobial peptides from marine organisms retain anticancer activity and antibacterial activity against multidrug-resistant Staphylococcus aureus PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0303783 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Sheep erythrocytes (50% Hemolysis at 400 microg/ml
400 μg/mL
Hemolysis
PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0379096 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Vibrio vulnificus 204
PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0388776 VERIFIED: YES
Provenance & Taxonomy
Epinephelus nebulosus [Animal]
Epinecidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HT-1080
6.25 μg/mL
Cytotoxicity assay
PaperTruncated antimicrobial peptides from marine organisms retain anticancer activity and antibacterial activity against multidrug-resistant Staphylococcus aureus PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
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