Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC428H666N120O119S12

DescriptionStandard

        MKAFSIAVAVTLVLAFVCIVESSALPFTGVPELGEAGGNDTPAAVHPDEPARSWMMPGHVREKRQSHLSLCRWCCNCCRSYKGCGFCCKF
    

Molecular Weight9781.38 Da

Isoelectric Point (pI)8.11

Net Charge (pH 7.0)1.68

Net Charge (pH 7.4) 1.17

Charge Density (pH 7.0) 0.0187

GRAVY Index0.20

Hydrophobic Moment 0.66

Boman Index0.12

Instability Index55.58

Aliphatic Index 70.44

Aromaticity 0.0889

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3744.58

LogP -36.86

H-bond Donors 139.0

H-bond Acceptors 136.0

Rotatable Bonds 309.0

Heavy Atoms 679.0

Ring Count 19.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0092723 VERIFIED: NO

Provenance & Taxonomy

OrganismNeogobius melanostomus [Animal]

FamilyHepcidin

Tax ID47308

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal