Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length416 amino acids

Chemical FormulaC2086H3298N558O593S8

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGMAILEKELAQLKLPDISGDSRVLRVGKVHYELSRLRLRDFHLPYSRITPVSNVGLQVSISNAFAELDGDWRVKFLFVRDHGSFNLKVENVYIKITLRLGSDTTGKPTISTSACSASISKVRVLFSGKLGWLYNLFHSVIESRLRKILEDKVCDNVAKSVHNDLQTYLQTLPVTARIDGKTGIDYSLVAPPRATAQSLDADLKGEFYSLAHRSTVPFSPLPLAFLSDHDRMVYFGASSYFFNTAGIAYHEAGALVFEITEAMIPKDVGFRLDTSVFSAFIPQLEEMYPNMPMKFRLSAPTAPFLTIGPGGISFQPIVDAQAYVILPDSSLAPLFLLSLVRNVSAVINVRSGHIVGSLDVGRIRLSLKDSAVGTFQVQSLQSIINYLTSRVVLPRLN
    

Molecular Weight45938.40 Da

Isoelectric Point (pI)9.15

Net Charge (pH 7.0)6.28

Net Charge (pH 7.4) 5.47

Charge Density (pH 7.0) 0.0151

GRAVY Index0.12

Hydrophobic Moment 0.66

Boman Index0.11

Instability Index36.97

Aliphatic Index 104.25

Aromaticity 0.0938

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 31985.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0380654 VERIFIED: NO

Provenance & Taxonomy

OrganismToxostoma redivivum [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria