Peptide Database

Peptide NameInsulin-like growth factor II

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC322H506N94O101S6

DescriptionStandard

        AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVNRRSRGIVEECCFRSCDLALLETYCATPAKSE
    

Molecular Weight7502.42 Da

Isoelectric Point (pI)6.46

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.54

Charge Density (pH 7.0) -0.0036

GRAVY Index-0.26

Hydrophobic Moment 0.87

Boman Index-0.10

Instability Index75.54

Aliphatic Index 65.52

Aromaticity 0.1045

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3163.64

LogP -36.02

H-bond Donors 120.0

H-bond Acceptors 107.0

Rotatable Bonds 243.0

Heavy Atoms 523.0

Ring Count 10.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0003889 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyInsulin-like growth factor

Tax ID9823

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide9-47; 21-60; 46-51

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0036770 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyInsulin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0119584 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyInsulin-like growth factor

Tax ID9823

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide9-47; 21-60; 46-51

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory

Targetglucose metabolism in adipose tissue

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour