Peptide Database

Peptide NameL-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Enzyme / Catalytic activity ▸ Oxidoreductase

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length107 amino acids

Chemical FormulaC561H815N139O173S5

DescriptionStandard

        ADDKNPLEECFREDDYEEFLEIAKNGLEGWYANLGPMRYPVKPSEEGKHDDIFAYEKFDEIVGGMDKKFWEDDGIHGGKETFCYSPMIQKPYQFQHFSEALTAPVGR
    

Molecular Weight12434.63 Da

Isoelectric Point (pI)4.52

Net Charge (pH 7.0)-11.93

Net Charge (pH 7.4) -12.35

Charge Density (pH 7.0) -0.1115

GRAVY Index-0.88

Hydrophobic Moment 0.56

Boman Index-0.07

Instability Index38.18

Aliphatic Index 50.19

Aromaticity 0.1495

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20065.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5000.16

LogP -39.75

H-bond Donors 167.0

H-bond Acceptors 169.0

Rotatable Bonds 408.0

Heavy Atoms 878.0

Ring Count 28.0

Amide Bonds 112.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0062331 VERIFIED: YES

Provenance & Taxonomy

OrganismMacrovipera lebetina [Animal]

FamilyFlavin monoamine oxidase; FIG1 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Oxidoreductase Antiplatelet Cytolytic Toxin Hemolytic

TargetNo Target Organism Found

RECORD: Rec_0079064 VERIFIED: YES

Provenance & Taxonomy

OrganismMacrovipera lebetina [Animal]

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

RECORD: Rec_0326995 VERIFIED: YES

Provenance & Taxonomy

OrganismMacrovipera lebetina [Animal]

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetBacillus subtilis