Peptide Database

Peptide NameCathelicidin-2 (Bactenecin-5) (Bac5) (ChBac5)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length176 amino acids

Chemical FormulaC892H1405N255O249S5

DescriptionStandard

        METQGASLSLGRWSLWLLLLGLVVPLASAQALSYREAVLRAVGQLNERSSEANLYRLLELDPAPNDEVDPGTRKPVSFTVKETVCPRTTQQPPEECDFKENGLVKQCVGTVTLDPSNDQFDINCNELQSVRFRPPIRRPPIRPPFNPPFRPPVRPPFRPPFRPPFRPPIGPFPGRR
    

Molecular Weight19845.58 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)4.49

Net Charge (pH 7.4) 4.19

Charge Density (pH 7.0) 0.0255

GRAVY Index-0.51

Hydrophobic Moment 0.70

Boman Index-0.09

Instability Index66.10

Aliphatic Index 76.93

Aromaticity 0.0795

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7978.11

LogP -88.77

H-bond Donors 269.0

H-bond Acceptors 259.0

Rotatable Bonds 613.0

Heavy Atoms 1401.0

Ring Count 45.0

Amide Bonds 191.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0043115 VERIFIED: YES

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyCathelicidin

Tax ID9925

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetListeria monocytogenes (Gram-positive)

RECORD: Rec_0083266 VERIFIED: YES

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyCathelicidin

Tax ID9925

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0224720 VERIFIED: YES

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyCathelicidin

Tax ID9925

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetS. typhimurium

RECORD: Rec_0422144 VERIFIED: YES

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyCathelicidin

Tax ID9925

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli (Gram-negative)