Peptide Database

Peptide NameS-type Pyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length497 amino acids

Chemical FormulaC2457H3850N686O734S15

DescriptionStandard

        MGRKLAGTLDSVSTCPCRARFINSEMDSYEKQDKAADRVVAPANIVMQSFSSPTKEAGSIQPKPSVTPTPPPPIPVFAKSCLRGKGCTDAGTEAEPADNFGRMAIYQVPSSPAPVTPQKPEPPPQGKQHPPEPDKSQDKKLPWYKRWFRDGEDKAEAAATSVAATARSAVAEGEGLVMRYIGGSAISAGRWLAAPNPVTIGLMGLFYSPKLNDGEEDYLTPYRLRQIAEQYGKASTRVRFRWIRDEKSGRITVQGYHVSPEGGLDKVPVRMMTLNRTTGNYEFWEPGEHRPTILWTPNEQEFKVPAHTGNEERPFIPSQITVLPIPDKVGSDIESFPMPEEKDFRDYILVLPIPNMPPVYVYLSKPPVKSLEVDLYRNFNGRLRGGMHADHIPSAAAVKAAAKRLNPTLAPKEQNKQVKDVAAIIIPSKVHQKYSETYGGRNTPEQIARDAKDLKQAVDNNFNAIKPYLEEEGFSEQELEQAHQKIHDINQKQGLYK
    

Molecular Weight55223.99 Da

Isoelectric Point (pI)8.57

Net Charge (pH 7.0)4.32

Net Charge (pH 7.4) 3.43

Charge Density (pH 7.0) 0.0087

GRAVY Index-0.66

Hydrophobic Moment 0.75

Boman Index-0.08

Instability Index52.26

Aliphatic Index 67.95

Aromaticity 0.0785

Extinction Coeff. Reduced 59820.00

Extinction Coeff. Oxidized 60070.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0412730 VERIFIED: YES

Provenance & Taxonomy

OrganismPhotorhabdus luminescens [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)