Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length241 amino acids

Chemical FormulaC1244H1882N276O366S8

DescriptionStandard

        IDDLAEVDYSLNSLPAVSRPFIDLDLKGIVYPAGNYTGPPYVAAPFTIPDQSDSMLYLAFSEYFFQTYSFAYYTAGAFNITIAEEVTYLFSRIFFFLQTCSYFNISTEIFGSIIPEVAEYSVTPYPVMLKLMATEIPIISLEEDSFTVEIQGTMEVFAVLPDSTTQSLFTMNIAANTSIALNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANAKLSKGLPLP
    

Molecular Weight26816.40 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-17.14

Net Charge (pH 7.4) -17.48

Charge Density (pH 7.0) -0.0711

GRAVY Index0.40

Hydrophobic Moment 0.61

Boman Index0.28

Instability Index47.03

Aliphatic Index 102.82

Aromaticity 0.1411

Extinction Coeff. Reduced 20860.00

Extinction Coeff. Oxidized 20985.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326150 VERIFIED: NO

Provenance & Taxonomy

OrganismLeptosomus discolor [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria