Peptide Database

Peptide NameAlpha-defensin 8 (Defensin-related cryptdin-8)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length81 amino acids

Chemical FormulaC382H612N118O132S8

DescriptionStandard

        LAFQVQADPIQNTDEETKTEEQPGEDDQAVSVSFGDPEGSSLQEESLRDLVCYCRKRGCKRREHMNGTCRKGHLMYTLCCR
    

Molecular Weight9226.18 Da

Isoelectric Point (pI)5.08

Net Charge (pH 7.0)-4.10

Net Charge (pH 7.4) -4.52

Charge Density (pH 7.0) -0.0506

GRAVY Index-0.96

Hydrophobic Moment 0.62

Boman Index-0.26

Instability Index54.25

Aliphatic Index 51.73

Aromaticity 0.0494

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4106.67

LogP -50.91

H-bond Donors 147.0

H-bond Acceptors 138.0

Rotatable Bonds 315.0

Heavy Atoms 640.0

Ring Count 9.0

Amide Bonds 88.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0375107 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic

TargetNo Target Organism Found