Peptide Database

Peptide NameGranulocyte-macrophage colony-stimulating factor

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length127 amino acids

Chemical FormulaC639H1007N171O196S8

DescriptionStandard

        APARSPSPSTQPWEHVNAIQEARRLLNLSRDTAAEMNETVEVISEMFDLQEPTCLQTRLELYKQGLRGSLTKLKGPLTMMASHYKQHCPPTPETSCATQIITFESFKENLKDFLLVIPFDCWEPVQE
    

Molecular Weight14477.38 Da

Isoelectric Point (pI)5.21

Net Charge (pH 7.0)-4.94

Net Charge (pH 7.4) -5.38

Charge Density (pH 7.0) -0.0389

GRAVY Index-0.45

Hydrophobic Moment 0.74

Boman Index-0.03

Instability Index66.86

Aliphatic Index 76.06

Aromaticity 0.0709

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5874.61

LogP -57.31

H-bond Donors 201.0

H-bond Acceptors 202.0

Rotatable Bonds 472.0

Heavy Atoms 1014.0

Ring Count 25.0

Amide Bonds 138.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0359417 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGM-CSF family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide54-96; 88-121

Bio-Activity Profile

Function

Cytokine Growth factor GM-CSF family Growth factor signaling