Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length453 amino acids

Chemical FormulaC2299H3612N612O631S12

DescriptionStandard

        TNPGFVVRITQAGLDYAHQHGIAILEKQLAQLRLPDISGDSRVLHMRKVHYELSRLRLRDFQLPFSRITPMAGVGLQISISNAFAELDGDWRVKFLFVRDHGSFNLKVENVYIKIILRLGSDTAGKPTVSSSDCSTRISNVQVLFSGKFGWLYNLFHSVIESRFRKILEDKVCDNVAKSVHTELQTYIQTLPVTAKIDAKTGIDYSLVAPPRAAAQSLDVDLKGEFYSLAHRSTAPFSPLPLAFPSDHDHMVYFGASSYFFNTAGFAYHKAGALVFEITEAMIPKDVGFSLNTSIFSAFVPQLEKMYPNMPMKFRLSTPTAPFLTIGPGGISLKPIVDAQAYAILPNSSLAPLFLLSLVRNVSAVINVRSGHIVGSLDVGRLKLFLPLSPPQVRMMQSLMNILASSTLLPRLNARLEEGFPLPLPDRIQLSNILVRFHQNFLLLGADVHFQPQ
    

Molecular Weight50305.77 Da

Isoelectric Point (pI)9.42

Net Charge (pH 7.0)9.63

Net Charge (pH 7.4) 8.62

Charge Density (pH 7.0) 0.0213

GRAVY Index0.12

Hydrophobic Moment 0.70

Boman Index0.13

Instability Index39.78

Aliphatic Index 102.67

Aromaticity 0.0971

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0201356 VERIFIED: NO

Provenance & Taxonomy

OrganismNotiomystis cincta [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria