Peptide Database

Peptide NameUnnamed

Function Ontology

Gastrointestinal bioactivity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC466H742N150O143S4

DescriptionStandard

        QPMPHADPTGPRAQQAEEAPRRQLRAVPRVDDEPRAQLGALLARYIQQARKAPSGRMSVIKNLQSLDPSHRISDRDYMGWMDFGRRSAEEFEYTS
    

Molecular Weight10862.06 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)1.95

Net Charge (pH 7.4) 1.63

Charge Density (pH 7.0) 0.0206

GRAVY Index-1.01

Hydrophobic Moment 0.86

Boman Index-0.27

Instability Index69.07

Aliphatic Index 57.68

Aromaticity 0.0632

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4764.97

LogP -53.82

H-bond Donors 165.0

H-bond Acceptors 151.0

Rotatable Bonds 356.0

Heavy Atoms 763.0

Ring Count 18.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0213321 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0342503 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyGastrin/cholecystokinin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsTyr77 Sulfotyrosine; Phe83 Amidation; Tyr93 Sulfotyrosine

Bio-Activity Profile

Function

Hormone Gastrointestinal Neuropeptide

RECORD: Rec_0411697 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyCholecystokinin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other Mods77:Sulfotyrosine; 83:Phenylalanine amide; 93:Sulfotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Myotropic Receptor modulation

TargetCCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour