‹ ›
MYP_113002
← PREVIOUS NEXT → BACK
Basic Information
Panitide L2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
28 amino acids
C130H209N37O38S6
Standard
Sequence
QLPICGETCVLGGCYTPNCRCQYPICVR
Physicochemical Analysis
3090.67 Da
7.77
0.70
0.41
0.0251
0.25
0.25
0.10
7.81
76.43
0.0714
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1193.94
-12.57
46.0
45.0
93.0
211.0
5.0
30.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0225027 VERIFIED: YES
Provenance & Taxonomy
Panicum laxum [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Pyroglutamate
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Cytotoxic
PMID23195955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23195955/
RECORD: Rec_0280949 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0283535 VERIFIED: YES
Provenance & Taxonomy
Panicum laxum [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Pyroglutamylation
N-terminus is a pyroglutamate (XXQ)
Bio-Activity Profile
Antimicrobial Anticancer
Escherichia coli ATCC 25922
2.5 μM
MIC
PaperDiscovery of linear cyclotides in monocot plant Panicum laxum of Poaceae family provides new insights into evolution and distribution of cyclotides in plants.
RECORD: Rec_0334523 VERIFIED: YES
Provenance & Taxonomy
Panicum laxum [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Pyroglutamate
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli ATCC 25922
2.5 μM
MIC
PMID23195955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23195955/
RECORD: Rec_0419059 VERIFIED: YES
Provenance & Taxonomy
Panicum laxum [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Pyroglutamate
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
N-terminal pyroglutamate
Bio-Activity Profile
Antimicrobial
Active against E. coli
2.5 μM
MIC
PaperDiscovery of linear cyclotides in monocot plant Panicum laxum of Poaceae family provides new insights into evolution and distribution of cyclotides in plants PMID23195955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23195955/
FIRST PREV 1 2
Showing 5 records on this page · Page 2 of 2