MYP_113002
Panitide L2
Anticancer
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Standard
28 amino acids
C130H209N37O38S6
Standard
QLPICGETCVLGGCYTPNCRCQYPICVR
3090.67 Da
7.77
0.70
0.41
0.0251
0.25
0.25
0.10
7.81
76.43
0.0714
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1193.94
-12.57
46.0
45.0
93.0
211.0
5.0
30.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0024004
VERIFIED: NO
Provenance & Taxonomy
Panicum laxum [Plant]
Cyclotide
Structure & Mods
disulfide-constrained linear cyclotide [Linear]
canonical L-amino-acid peptide [L]
Pyroglutamylation
Free
Three disulfide bonds reported, sites unresolved
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0139580
VERIFIED: YES
Provenance & Taxonomy
Panicum laxum [Plant]
Structure & Mods
disulfide-constrained linear cyclotide [Linear]
canonical L-amino-acid peptide [L]
Pyroglutamylation
Free
Three disulfide bonds reported, sites unresolved
N-terminus is a pyroglutamate (XXQ)
Bio-Activity Profile
Antimicrobial
Anticancer
Cytotoxic
HeLa cells
6.0 μM
IC50
RECORD: Rec_0157568
VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0283535
VERIFIED: YES
Provenance & Taxonomy
Panicum laxum [Plant]
Structure & Mods
disulfide-constrained linear cyclotide [Linear]
canonical L-amino-acid peptide [L]
Pyroglutamylation
Free
Three disulfide bonds reported, sites unresolved
N-terminus is a pyroglutamate (XXQ)
Bio-Activity Profile
Antimicrobial
Anticancer
Escherichia coli ATCC 25922
2.5 μM
MIC