Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length126 amino acids

Chemical FormulaC691H1025N179O171S8

DescriptionStandard

        MYNAQGFKLYLEGQAQKRALTPFFWKWKLPSSFRFLLYSPTHPTSLTAKWKLISIIVIFFWPGKHPILRCMGNIGVCRPSCKKNEQPYYYCRNYQPCCLQSYVRISITGAEGNNDWSYGNHWPKIP
    

Molecular Weight14832.15 Da

Isoelectric Point (pI)9.67

Net Charge (pH 7.0)11.69

Net Charge (pH 7.4) 11.20

Charge Density (pH 7.0) 0.0928

GRAVY Index-0.36

Hydrophobic Moment 0.60

Boman Index0.05

Instability Index43.10

Aliphatic Index 69.68

Aromaticity 0.1746

Extinction Coeff. Reduced 46410.00

Extinction Coeff. Oxidized 46785.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5591.17

LogP -40.38

H-bond Donors 199.0

H-bond Acceptors 194.0

Rotatable Bonds 464.0

Heavy Atoms 1049.0

Ring Count 42.0

Amide Bonds 138.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0146884 VERIFIED: NO

Provenance & Taxonomy

OrganismHeterocephalus glaber [Animal]

FamilyDefensin

Tax ID10181

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

RECORD: Rec_0146901 VERIFIED: NO