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MYP_112943
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Basic Information
RW4
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Antiviral
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Delivery / Targeting ▸ Targeting ligand ▸ Targeting
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
8 amino acids
C68H90N24O9
Standard
Sequence
RWRWRWRW
Physicochemical Analysis
1387.60 Da
12.00
3.76
3.56
0.4700
-2.70
0.23
-0.86
295.15
0.00
0.5000
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
577.78
-0.26
25.0
13.0
39.0
101.0
8.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0281127 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antibiofilm Antibacterial
Escherichia coli HM22
20 μM
Total countable CFUs
RECORD: Rec_0292361 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Doxorubicin (Dox) is a well-known anthracycline which has been conjugated to a CPP
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Doxorubicin (Dox) which is anthracycline attached with linker to CPP [W(RW)4 ]
Bio-Activity Profile
Anticancer
HCT-116
1 μM
Concentration response
PMID23301519 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23301519/
RECORD: Rec_0306724 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0320722 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Sheep erythrocytes
2 μM
Paperhttps://pubmed.ncbi.nlm.nih.gov/17145799/ PMID17145799 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17145799/
RECORD: Rec_0352020 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Doxorubicin (Dox) which is anthracycline attached with linker to CPP [W(RW)4 ]
Bio-Activity Profile
Anticancer
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
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