Peptide Database

Peptide NameAntimicrobial peptide HsAp2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC369H629N107O106S6

DescriptionStandard

        MSRRLILILVLVAMLVKTMAGMESKWVETTYEIKKRSGTSEKERESERLLGVVNPLIKCFRSPCPGRRAISEQT
    

Molecular Weight8452.99 Da

Isoelectric Point (pI)9.91

Net Charge (pH 7.0)5.50

Net Charge (pH 7.4) 5.23

Charge Density (pH 7.0) 0.0743

GRAVY Index-0.18

Hydrophobic Moment 0.68

Boman Index-0.09

Instability Index76.39

Aliphatic Index 96.08

Aromaticity 0.0405

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3475.93

LogP -32.00

H-bond Donors 128.0

H-bond Acceptors 118.0

Rotatable Bonds 293.0

Heavy Atoms 588.0

Ring Count 7.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0116035 VERIFIED: YES

Provenance & Taxonomy

OrganismHeterometrus spinifer [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetGram-negative and Gram-positive bacteria