Peptide Database

Peptide NameBeta-defensin 9

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC366H581N101O100S10

DescriptionStandard

        MRTLCSLLLICCLLFSYDTPVVGELKHLGLKTEFEQCQRIRGYCLNTYCRFPTSHVGSCYPEKRYCCKNIR
    

Molecular Weight8316.80 Da

Isoelectric Point (pI)8.80

Net Charge (pH 7.0)4.59

Net Charge (pH 7.4) 4.12

Charge Density (pH 7.0) 0.0646

GRAVY Index-0.05

Hydrophobic Moment 0.56

Boman Index-0.02

Instability Index33.23

Aliphatic Index 83.66

Aromaticity 0.1127

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3248.87

LogP -28.35

H-bond Donors 125.0

H-bond Acceptors 117.0

Rotatable Bonds 272.0

Heavy Atoms 577.0

Ring Count 13.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0238774 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q32ZI2/entry; https://bblserver.org.in/ampdb/