Peptide Database

Peptide NameCD-NP (C-terminal tail of DNP)

Function Ontology

Natriuretic

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC158H265N49O50S3

DescriptionStandard

        GLSKGCFGLKLDRIGSMSGLGCPSLRDPRPNAPSTSA
    

Molecular Weight3747.29 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.0741

GRAVY Index-0.25

Hydrophobic Moment 0.45

Boman Index-0.02

Instability Index41.88

Aliphatic Index 68.65

Aromaticity 0.0270

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1572.80

LogP -21.96

H-bond Donors 57.0

H-bond Acceptors 56.0

Rotatable Bonds 121.0

Heavy Atoms 260.0

Ring Count 5.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0258934 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyNatriuretic peptide

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide6-22

Bio-Activity Profile

Function

Natriuretic

Half-LifeHuman kidney membrane extract, in vitro; 1197 s