Peptide Database

Peptide NameChaC2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Insecticidal/Pest control ▸ Insecticidal activity

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC135H212N40O40S8

DescriptionStandard

        GVPCGESCVWMYCISAAMGCSCRNKVCYRN
    

Molecular Weight3291.89 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0567

GRAVY Index0.25

Hydrophobic Moment 0.32

Boman Index0.08

Instability Index60.14

Aliphatic Index 48.67

Aromaticity 0.1000

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1288.67

LogP -15.13

H-bond Donors 52.0

H-bond Acceptors 50.0

Rotatable Bonds 103.0

Heavy Atoms 223.0

Ring Count 5.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0081582 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

RECORD: Rec_0181920 VERIFIED: YES

Provenance & Taxonomy

OrganismPetunia x hybrida [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Insecticidal