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MYP_112708
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Basic Information
Toxin F-VIII
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
60 amino acids
C277H462N82O84S10
Standard
Sequence
MICYSHKTPQPSATITCEEKTCYKKSVRKLPAIVAGRGCGCPSKEMLVAIHCCRSDKCNE
Physicochemical Analysis
6605.78 Da
8.87
4.60
4.15
0.0767
-0.33
0.63
-0.10
45.40
60.17
0.0333
2980.00
3480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2665.47
-30.73
101.0
101.0
220.0
453.0
8.0
61.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0015936 VERIFIED: YES
Provenance & Taxonomy
venom of the Eastern green mamba,Dendroaspis angusticeps [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HT-29
300 μg/mL
LC50
PaperPubMed PMID: 25035794 PMID25035794 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25035794/
RECORD: Rec_0110328 VERIFIED: YES
Provenance & Taxonomy
venom of the Eastern green mamba,Dendroaspis angusticeps [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-231
300 μg/mL
LC50
PaperPubMed PMID: 25035794 PMID25035794 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25035794/
RECORD: Rec_0285124 VERIFIED: YES
Provenance & Taxonomy
venom of the Eastern green mamba,Dendroaspis angusticeps [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
A549
106±5 μg/mL
LC50
PaperPubMed PMID: 25035794 PMID25035794 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25035794/
RECORD: Rec_0312833 VERIFIED: YES
Provenance & Taxonomy
venom of the Eastern green mamba,Dendroaspis angusticeps [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
1000 μg/mL
LC50
PaperPubMed PMID: 25035794 PMID25035794 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25035794/
RECORD: Rec_0356669 VERIFIED: YES
Provenance & Taxonomy
venom of the Eastern green mamba,Dendroaspis angusticeps [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
HUVEC
300 μg/mL
LC50
PaperPubMed PMID: 25035794 PMID25035794 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25035794/