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MYP_112690
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Basic Information
M-zodatoxin-Lt1a (M-ZDTX-Lt1a; Latarcin-1, Ltc-1, Ltc1; spiders, Arthropods, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
25 amino acids
C138H238N44O31S2
Standard
Sequence
SMWSGMWRRKLKKLRNALKKKLKGE
Physicochemical Analysis
3073.77 Da
11.77
8.46
8.24
0.3384
-1.25
0.69
-0.45
18.36
66.40
0.0800
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1281.99
-9.13
48.0
42.0
114.0
215.0
4.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0095442 VERIFIED: YES
Provenance & Taxonomy
Lachesana tarabaevi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
rabbit erythrocytes
PMID16735513;18293934 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16735513/
RECORD: Rec_0127385 VERIFIED: YES
Provenance & Taxonomy
Lachesana tarabaevi [Animal]
Latarcin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Pseudomonas aeruginosa
4.1 μM
MIC
PaperLatarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity. PMID16735513 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16735513/
RECORD: Rec_0150547 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Rabbit erythrocytes
80 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/16735513/ PMID16735513 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16735513/
RECORD: Rec_0153841 VERIFIED: YES
Provenance & Taxonomy
Lachesana tarabaevi [Animal]
Latarcin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli MH1
0.7 μM
MIC
PMID16735513 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16735513/
RECORD: Rec_0158654 VERIFIED: YES
Provenance & Taxonomy
Lachesana tarabaevi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PMID16735513;18293934 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16735513/
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