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MYP_112674
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Basic Information
D2-NH2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
10 amino acids
C63H101N21O12
Standard
Sequence
SGKLWWRRKK
Physicochemical Analysis
1344.61 Da
12.00
4.46
4.25
0.4457
-1.99
0.32
-0.66
72.98
39.00
0.2000
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
578.89
-3.21
23.0
17.0
46.0
96.0
4.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0260010 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (2% Hemolysis at 100 microM, Human erythrocytes (3% Hemolysis at 100 microM
100 μM
Hemolysis
PMID23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23860860/
RECORD: Rec_0293805 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
12
MIC
PMID23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23860860/
RECORD: Rec_0306086 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
6±0.012 μM
MIC
PaperPubMed PMID: 22518150 | PubMed PMID: 23860860 PMID22518150;23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22518150/
RECORD: Rec_0340413 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PaperPubMed PMID: 22518150 | PubMed PMID: 23860860 PMID22518150;23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22518150/
RECORD: Rec_0373969 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
12
MIC
PMID23860860 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23860860/
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