Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC387H599N107O102S11

DescriptionStandard

        CNGEPLSPVPAPPGQGCPLLTTICSVFFVSGDAQKCWNLHGKCRHRCSRKESVYVYCTNGKMCCVKPKYQPKPKPWMF
    

Molecular Weight8735.27 Da

Isoelectric Point (pI)9.20

Net Charge (pH 7.0)7.84

Net Charge (pH 7.4) 7.39

Charge Density (pH 7.0) 0.1005

GRAVY Index-0.38

Hydrophobic Moment 0.40

Boman Index-0.02

Instability Index41.89

Aliphatic Index 49.87

Aromaticity 0.1026

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3291.89

LogP -31.84

H-bond Donors 119.0

H-bond Acceptors 123.0

Rotatable Bonds 271.0

Heavy Atoms 607.0

Ring Count 22.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0148578 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence