Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length228 amino acids

Chemical FormulaC1155H1761N265O345S6

DescriptionStandard

        IDDLAEVDYSLNSLPAVFQPFIDLDLKGIVYPAGNYTGPPYVAAPFTIPDQSDSMLHLAFSEYFFQTSSFAYYTAGAFSITIAEETCSYFNISTEIFGSIIPEVAKYSVTRYPVMLKLTATEIPIISLEQDSFTVEIRGSMEVFAVLPDSSTQSLFTVNVAANTSIALNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight25071.30 Da

Isoelectric Point (pI)4.25

Net Charge (pH 7.0)-14.05

Net Charge (pH 7.4) -14.44

Charge Density (pH 7.0) -0.0616

GRAVY Index0.35

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index42.77

Aliphatic Index 101.40

Aromaticity 0.1272

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0354266 VERIFIED: NO

Provenance & Taxonomy

OrganismHaliaeetus albicilla [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria