Peptide Database

Peptide NameIndolicidin [W4K,W6K,W8K,W9K,W11K]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC75H141N25O14

DescriptionStandard

        ILPKKKPKKPKRR
    

Molecular Weight1617.08 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)7.75

Net Charge (pH 7.4) 7.54

Charge Density (pH 7.0) 0.5965

GRAVY Index-2.22

Hydrophobic Moment 0.50

Boman Index-0.87

Instability Index96.40

Aliphatic Index 60.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 666.07

LogP -3.87

H-bond Donors 23.0

H-bond Acceptors 22.0

Rotatable Bonds 58.0

Heavy Atoms 114.0

Ring Count 3.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0136129 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman red blood cells

Activity100 % hemolysis at >1000 μM

MethodHemolysis

RECORD: Rec_0236842 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetMicrococcus luteus ATCC 9341

Activity100 μM

MethodMIC