Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Anti-HIV ▸ HIV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC108H151N25O31S

DescriptionStandard

        SWLRDIWDWECEVLSDFK
    

Molecular Weight2327.57 Da

Isoelectric Point (pI)4.10

Net Charge (pH 7.0)-3.54

Net Charge (pH 7.4) -3.77

Charge Density (pH 7.0) -0.1968

GRAVY Index-0.48

Hydrophobic Moment 0.57

Boman Index-0.00

Instability Index38.87

Aliphatic Index 81.11

Aromaticity 0.2222

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 920.27

LogP -3.69

H-bond Donors 34.0

H-bond Acceptors 29.0

Rotatable Bonds 73.0

Heavy Atoms 165.0

Ring Count 7.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0272076 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-Term-

C-Term-

Bio-Activity Profile

Function

Antimicrobial Antiviral Hemolytic

RECORD: Rec_0315422 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyProtein-derived synthetic peptide

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-Term-

C-Term-

Bio-Activity Profile

Function

Antiviral Anti-HIV-1 Infection inhibition

TargetHIV-1 | TZM-BL cells

Activity5 μM

MethodIC50

Half-LifeMammalian: 1.9 h; Yeast: >20 h; E. coli: >10 h

PaperRational design of peptides with anti-HCV/HIV activities and enhanced specificity. | Li GR, He LY, Liu XY, Liu AP, Huang YB, Qiu C, Zhang XY, Xu JQ, Yang W, Chen YX. | Chem Biol Drug Des. 2011 Nov;78(5):835-43. | DOI:10.1111/j.1747-0285.2011.01201.x | PMID:21801309 PMID21801309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21801309/

RECORD: Rec_0418473 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyProtein-derived synthetic peptide

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-Term-

C-Term-

Bio-Activity Profile

Function

Antiviral Anti-HCV Infection inhibition

TargetHCV | Huh7.5.1 cells

Activity5 μM

MethodIC50

Half-LifeMammalian: 1.9 h; Yeast: >20 h; E. coli: >10 h

PaperRational design of peptides with anti-HCV/HIV activities and enhanced specificity. | Li GR, He LY, Liu XY, Liu AP, Huang YB, Qiu C, Zhang XY, Xu JQ, Yang W, Chen YX. | Chem Biol Drug Des. 2011 Nov;78(5):835-43. | DOI:10.1111/j.1747-0285.2011.01201.x | PMID:21801309 PMID21801309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21801309/

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