Peptide Database

Peptide NameVenturamide A

Function Ontology

Antimicrobial

Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial

Antiparasitic ▸ Antimalarial

Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium

Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC21H38N6O8S2

DescriptionStandard

        ATACVC
    

Molecular Weight566.69 Da

Isoelectric Point (pI)5.55

Net Charge (pH 7.0)-0.22

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0373

GRAVY Index2.02

Hydrophobic Moment 0.15

Boman Index0.47

Instability Index69.00

Aliphatic Index 81.67

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 229.05

LogP -3.24

H-bond Donors 10.0

H-bond Acceptors 10.0

Rotatable Bonds 15.0

Heavy Atoms 37.0

Ring Count 0.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0014563 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyVenturamide A

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Other Mods1-Oxazole, 2-thiazole

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Anti-Trypanosoma cruzi

TargetTrypanosoma cruzi

Activity14.6 μM

MethodIC50; ELISA

RECORD: Rec_0150909 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Other Mods1-Oxazole, 2-thiazole

Bio-Activity Profile

Function

Antiparasitic Antimicrobial Antiplasmodial Antitrypanosomal Antileishmanial Cyanobactins

RECORD: Rec_0155911 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyVenturamide A

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Other Mods1-Oxazole, 2-thiazole

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Antimalarial

TargetPlasmodium falciparum W2

Activity8.2 μM

MethodIC50; Fluorimetry (PicoGreen)

RECORD: Rec_0292252 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyVenturamide A

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Other Mods1-Oxazole, 2-thiazole

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Antileishmanial

TargetLeishmania donovani

Activity>20 μM

MethodIC50; Fluorimetry (PicoGreen)