Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length120 amino acids

Chemical FormulaC621H991N181O167S10

DescriptionStandard

        MLQTRSSTLSGHNKLWFLTLAVLVVLAQTSPEGWFRTCFYGLGKCRRICRANEKKKERCGERTFCCLRETNSRLSHIPVTKDREKDGMYLFQTSGFRALVVIMTSWGHIQYPMLELLRVH
    

Molecular Weight13985.27 Da

Isoelectric Point (pI)9.78

Net Charge (pH 7.0)9.80

Net Charge (pH 7.4) 9.27

Charge Density (pH 7.0) 0.0817

GRAVY Index-0.23

Hydrophobic Moment 0.69

Boman Index-0.06

Instability Index48.89

Aliphatic Index 82.00

Aromaticity 0.1000

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5649.04

LogP -51.37

H-bond Donors 211.0

H-bond Acceptors 191.0

Rotatable Bonds 468.0

Heavy Atoms 979.0

Ring Count 22.0

Amide Bonds 126.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0017066 VERIFIED: NO

Provenance & Taxonomy

OrganismMus spicilegus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence