Peptide Database

Peptide NameUrokinase

Function Ontology

Anticancer

Hemostasis ▸ Anticoagulant activity

Hemostasis ▸ Fibrinolytic activity

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length276 amino acids

Chemical FormulaC1376H2145N383O406S18

DescriptionStandard

        KPSSPPEELKFQCGQKTLRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLMSPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEENGLAL
    

Molecular Weight31126.24 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)6.45

Net Charge (pH 7.4) 5.54

Charge Density (pH 7.0) 0.0234

GRAVY Index-0.47

Hydrophobic Moment 0.51

Boman Index-0.03

Instability Index44.98

Aliphatic Index 70.29

Aromaticity 0.0942

Extinction Coeff. Reduced 45380.00

Extinction Coeff. Oxidized 46130.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0005563 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyEnzyme

Tax ID9606

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsLipidation

Bio-Activity Profile

Function

Anticancer Enzyme replacement Anticoagulant Thrombolytic Fibrinolytic

Half-Life12.6±6.2 minutes