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MYP_112488
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Basic Information
O-17 (Oncocin)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxicity
not Standard
19 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
VDKPPYLPRPRPPRXIYNX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
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0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0073777 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
ornithine at 15,19
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli 205024
1 μg/mL
PMID20565063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20565063/
RECORD: Rec_0076324 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
ornithine at 15,19
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
K. pneumoniaeATCC 43816
16 μg/mL
MIC
PMID25968331 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25968331/
RECORD: Rec_0087589 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
ornithine at 15,19
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
E. cloacae 34654
0.5 μg/mL
PMID20565063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20565063/
RECORD: Rec_0101355 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
ornithine at 15,19
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Klebsiella pneumoniae 63
2 μg/mL
PMID20565063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20565063/
RECORD: Rec_0103773 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
ornithine at 15,19
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
P. vulgaris ICB9095
4 μg/mL
PMID20565063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20565063/
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