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MYP_112488
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Basic Information
O-17 (Oncocin)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxicity
not Standard
19 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
VDKPPYLPRPRPPRXIYNX
Physicochemical Analysis
0.00 Da
0.00
0.00
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0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0390549 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
ornithine at 15,19; C-terminal amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Enterobacter cloacae Ha89
0.25 μg/mL
MIC
PaperOncocin (VDKPPYLPRPRPPRRIYNR-NH2): a novel antibacterial peptide optimized against Gram-negative human pathogens PMID20565063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20565063/
RECORD: Rec_0397970 VERIFIED: YES
Provenance & Taxonomy
Oncopeltus fasciatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 15,19
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli BL21
54
MIC
PMID26448548 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26448548/
RECORD: Rec_0403149 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
ornithine at 15,19; C-terminal amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Stenotrophomonas ICB7569
16 μg/mL
MIC
PaperOncocin (VDKPPYLPRPRPPRRIYNR-NH2): a novel antibacterial peptide optimized against Gram-negative human pathogens PMID20565063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20565063/
RECORD: Rec_0414931 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
ornithine at 15,19; C-terminal amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Stenotrophomonas ICB7789
32 μg/mL
MIC
PaperOncocin (VDKPPYLPRPRPPRRIYNR-NH2): a novel antibacterial peptide optimized against Gram-negative human pathogens PMID20565063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20565063/
RECORD: Rec_0415723 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
ornithine at 15,19; C-terminal amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Enterobacter cloacae Ha089
0.25 μg/mL
MIC
PaperOncocin (VDKPPYLPRPRPPRRIYNR-NH2): a novel antibacterial peptide optimized against Gram-negative human pathogens PMID20565063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20565063/
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