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MYP_112488
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Basic Information
O-17 (Oncocin)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxicity
not Standard
19 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
VDKPPYLPRPRPPRXIYNX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0343871 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
ornithine at 15,19
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Acinetobacter baumannii ICB9250
0.5 μg/mL
PMID20565063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20565063/
RECORD: Rec_0351514 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
ornithine at 15,19
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Klebsiella pneumoniae 57 USA
0.5 μg/mL
PMID20565063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20565063/
RECORD: Rec_0355582 VERIFIED: YES
Provenance & Taxonomy
Oncopeltus [Animal]
Oncocin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Orn=Ornithine
Bio-Activity Profile
Antimicrobial
8 μg/mL
MIC
Full mouse serum, in vivo; 10560 s
PaperBactericidal oncocin derivatives with superior serum stabilities PMID21185160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21185160/
RECORD: Rec_0359274 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
ornithine at 15,19
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Acinetobacter baumannii ICB14067
1 μg/mL
PMID20565063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20565063/
RECORD: Rec_0371371 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
ornithine at 15,19
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Acinetobacter baumannii ICB14072
1 μg/mL
PMID20565063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20565063/
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