Peptide Database

Peptide NameTemporin-GHa

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC56H93N17O16

DescriptionStandard

        LQHTTGALGHLI
    

Molecular Weight1260.44 Da

Isoelectric Point (pI)6.92

Net Charge (pH 7.0)-0.07

Net Charge (pH 7.4) -0.37

Charge Density (pH 7.0) -0.0055

GRAVY Index0.47

Hydrophobic Moment 0.28

Boman Index0.37

Instability Index15.90

Aliphatic Index 138.33

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 524.33

LogP -4.84

H-bond Donors 18.0

H-bond Acceptors 18.0

Rotatable Bonds 40.0

Heavy Atoms 89.0

Ring Count 2.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0178927 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana guentheri [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetEscherichia coli ATCC 44752

Activity13.3 μM

MethodMIC

RECORD: Rec_0231899 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana guentheri [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetStaphylococcus aureus ATCC 25923

Activity6.8 μM

MethodMIC

RECORD: Rec_0340043 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana guentheri [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetCandida albicans

Activity26.6 μM

MethodMIC

RECORD: Rec_0380651 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana guentheri [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetMethicillin-resistant Staphylococcus aureus ATCC 43300

Activity26.6 μM

MethodMIC