Peptide Database

Peptide NameColicin-E5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length180 amino acids

Chemical FormulaC850H1360N262O279S5

DescriptionStandard

        RFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDAAAKEKADADAALSTAMESRKKKEDNKRDAEGKLNDELAKNKGKIPGLKIDQKIRGQMPERGWTEDDIKNTVSNGATGTSFDKRSPKKTPPDYLGRNDPATVYGSPGKYVVVNDRTGEVTQISDKTDPGWVDDSRIQWGNKNDQ
    

Molecular Weight19873.81 Da

Isoelectric Point (pI)9.16

Net Charge (pH 7.0)3.96

Net Charge (pH 7.4) 3.59

Charge Density (pH 7.0) 0.0220

GRAVY Index-1.18

Hydrophobic Moment 0.49

Boman Index-0.26

Instability Index27.50

Aliphatic Index 49.44

Aromaticity 0.0556

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8892.21

LogP -110.27

H-bond Donors 302.0

H-bond Acceptors 290.0

Rotatable Bonds 681.0

Heavy Atoms 1396.0

Ring Count 25.0

Amide Bonds 199.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0112591 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyColicin/Pyocin

Tax ID562

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal

TargetEscherichia coli

MethodQualitative functional evidence