Peptide Database

Peptide NameM-lycotoxin-Ls3a (M-LCTX-Ls3a) (Lycocitin-1)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC89H153N23O24S

DescriptionStandard

        GKLQAFLAKMKEIAAQTL
    

Molecular Weight1961.37 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0978

GRAVY Index0.25

Hydrophobic Moment 0.41

Boman Index0.13

Instability Index46.93

Aliphatic Index 108.89

Aromaticity 0.0556

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 779.79

LogP -5.31

H-bond Donors 26.0

H-bond Acceptors 27.0

Rotatable Bonds 70.0

Heavy Atoms 137.0

Ring Count 1.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0074255 VERIFIED: YES

Provenance & Taxonomy

OrganismLycosa singoriensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli ATCC25922

Activity3

MethodMIC

RECORD: Rec_0077176 VERIFIED: YES

Provenance & Taxonomy

OrganismLycosa singoriensis [Animal]

FamilyCationic peptide 04 (cupiennin); 05 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetPseudomonas aeruginosa

RECORD: Rec_0142628 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct based on Lycosa singoriensis [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetStaphylococcus aureus, Bacillus subtilis, Gram-negative Escherichia coli, Pseudomonas aeruginosa

RECORD: Rec_0144364 VERIFIED: YES

Provenance & Taxonomy

OrganismLycosa singoriensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

RECORD: Rec_0157456 VERIFIED: YES

Provenance & Taxonomy

OrganismLycosa singoriensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetStaphylococcus aureus

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