Peptide Database

Peptide NameCycloviolacin H2

Function Ontology

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Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC136H197N37O39S6

DescriptionStandard

        NGIACGESCAYFGCWIPGCSCRNKVCYFN
    

Molecular Weight3166.63 Da

Isoelectric Point (pI)7.77

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.40

Charge Density (pH 7.0) 0.0242

GRAVY Index0.23

Hydrophobic Moment 0.26

Boman Index0.18

Instability Index59.89

Aliphatic Index 43.79

Aromaticity 0.1724

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1220.53

LogP -13.65

H-bond Donors 48.0

H-bond Acceptors 46.0

Rotatable Bonds 96.0

Heavy Atoms 218.0

Ring Count 7.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0377073 VERIFIED: YES

Provenance & Taxonomy

OrganismPigea floribunda [Plant]

FamilyCyclotide

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)